Management of hormonal therapy for the treatment of advanced hormone-dependent prostate cancer: A pharmacoeconomics assessment of the use of Degarelix – Firmagon® compared to generic triptorelin

  • Edgardo Salinas Alva Miembro de la Sociedad Peruana de Oncología Médica
  • Ebert Poquioma Rojas Instituto Nacional de Enfermedades Neoplásicas
  • Rosina Hinojosa Ramírez Universidad Pompeu Fabra Barcelona
Keywords: prostate, prostatic neoplasms, prostatic diseases

Abstract

Objective: This is a pharmacoeconomic evaluation of two therapy schedules using drugs with different modes of action: Degarelix and triptorelin in the treatment of patients with advanced hormone-dependent prostate cancer.

Methods: We reviewed the literature on the standard treatment for these patients, early and late effects of existing therapies, and we also performed a valuation using the Comprehensive Cost Treatment EsSalud (Peruvian Social Security) rates.

Results: The Comprehensive Cost Treatment is S/. 10 793 for a patient using Degarelix and S/. 12 251 for a patient using generic triptorelin, so the therapy with the GnRH antagonist generates S/. 1 458 savings per patient.

Conclusions: This represents S/. 1,008,017 savings for all patients with advanced hormone-dependent prostate who attend to EsSalud, with the added advantage that there are no extra costs with the use of Degarelix because of the absence of complications due to any flare effect.

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Published
2024-05-20
How to Cite
1.
Salinas Alva E, Poquioma Rojas E, Hinojosa Ramírez R. Management of hormonal therapy for the treatment of advanced hormone-dependent prostate cancer: A pharmacoeconomics assessment of the use of Degarelix – Firmagon® compared to generic triptorelin. Acta Med Peru [Internet]. 2024May20 [cited 2024Sep.11];28(4):188-93. Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/1118
Issue
Vol 28 No 4 (2011)
Section
ORIGINAL ARTICLES
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