Rol de las Vesículas Seminales en la Infertilidad Masculina

Abstract

The present study has been designed to determine any association between serum testosterone response to clomiphene citrate and the subsequent response of the seminal vesicles. Furthermore, it has been proposed to determine any association between seminal vesicles response and sperm motility, seminal viscosity, and sperm chromatin stability in semen. There were studied 42 male partners in infertile couples attending the Andrology laboratory because they or their wives were infertile, whose received clomiphene citrate two tablets a day during five days. True corrected seminal fructose was the best marker of seminal vesicles function than corrected seminal fructose or seminal fructose. Main cause of hypofunction of the seminal vesicles was leucocytospermia and/or history of sexual transmitted diseases (STD); in minor magnitude was observed hypoandrogenism as cause of hypofunction of the seminal vesicles. Prevalence of high semen viscosity, asthenozoospermia, and high sperm chromatin stability after SDS+EDTA were significantly reduced after clomiphene citrate treatment only when seminal vesicles were responsive to androgen stimulation. In conclusion, hypofunction of the seminal vesicles has important role determining mal e infertility, and clomiphene citrate may be u sed in these cases as diagnosis as well as therapeutic tools.