Cranial base chondrosarcoma: Clinicopathological analysis of a case

Keywords: Cranial base neoplasms, Chondrosarcoma, Immunohistochemistry

Abstract

Introduction:Chondrosarcoma is an unusual malignant neoplasm; cranial location is rare. Sometimes its complete resection is not possible because of vicinity of the mass to important vascular and neural structures.

Clinical case: This is a 56-year old female subject who developed headache in the right side, paresthesia in the right side of her upper lip, short term memory loss, and ageusia. A magnetic resonance imaging study showed an enhanced extra-axial mass. This patient underwent complete surgical resection. The anatomopathological study showed a well differentiated chondrosarcoma of the cranial base.

Conclusion: Chondrosarcoma is a malignancy with pure differentiation of the hyaline cartilage. It represents 0.15% of all intracranial tumors, and this is the second case with a cranial base location reported in Peru. Both histological characteristics and immunohistochemistry markers revealed the classic characteristics of this tumor. Therapy is given on an individualized basis.

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Author Biography

Alejandro Castillo, Hospital Nacional Alberto Sabogal Sologuren

Neurosurgeon of the Department of Neurosurgery of the Alberto Sabogal Sologuren National Hospital

Published
2021-10-24
How to Cite
1.
Romero Yauri J, Castillo Gutierrez AE, Castillo Soto AL. Cranial base chondrosarcoma: Clinicopathological analysis of a case. Acta Med Peru [Internet]. 2021Oct.24 [cited 2021Dec.5];38(3). Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/2145
Section
CASE REPORTS