Cranial base chondrosarcoma: Clinicopathological analysis of a case

Keywords: Cranial base neoplasms, Chondrosarcoma, Immunohistochemistry


Introduction:Chondrosarcoma is an unusual malignant neoplasm; cranial location is rare. Sometimes its complete resection is not possible because of vicinity of the mass to important vascular and neural structures.

Clinical case: This is a 56-year old female subject who developed headache in the right side, paresthesia in the right side of her upper lip, short term memory loss, and ageusia. A magnetic resonance imaging study showed an enhanced extra-axial mass. This patient underwent complete surgical resection. The anatomopathological study showed a well differentiated chondrosarcoma of the cranial base.

Conclusion: Chondrosarcoma is a malignancy with pure differentiation of the hyaline cartilage. It represents 0.15% of all intracranial tumors, and this is the second case with a cranial base location reported in Peru. Both histological characteristics and immunohistochemistry markers revealed the classic characteristics of this tumor. Therapy is given on an individualized basis.


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Author Biography

Alejandro Castillo, Departamento de Neurocirugía. Hospital Nacional Alberto Sabogal Sologuren. Callao, Perú

Neurosurgeon of the Department of Neurosurgery of the Alberto Sabogal Sologuren National Hospital

How to Cite
Romero Yauri J, Castillo Gutierrez AE, Castillo-Soto A. Cranial base chondrosarcoma: Clinicopathological analysis of a case. Acta Med Peru [Internet]. 2021Oct.24 [cited 2024Apr.19];38(3). Available from: