Clinical and demographic characteristics of an adult population with neuroendocrine tumors

Keywords: Neuroendocrine Carcinoma, Neuroendocrine tumors

Abstract

Introduction: Neuroendocrine tumors represent a group of low-incidence neoplasms derived from neuroendocrine cells distributed throughout the body, especially the respiratory and gastrointestinal systems.

Objective: To determine the clinical and sociodemographic characteristics of an adult population with neuroendocrine tumors.

Materials and methods: In a descriptive cross-sectional study, 91 medical records with a diagnosis of neuroendocrine tumors confirmed by pathology were evaluated between the years 2013 and 2020. Analysis carried out in Microsoft Excel 2013 and Epi Info 7.2.

Results: The mean age was 61 years, with a predominance in men (57%). The main antecedents were smoking (35%), arterial hypertension (22%), and COPD (9%). The main symptoms were abdominal pain (43%), weight loss (31%), and cough (26%).

According to the origin, those of the foregut were more frequent (75%), predominantly those of the respiratory tract (39.5%). In 21.9%, the origin was unknown.

Taking into account 2019 WHO classification, neuroendocrine carcinomas predominated (56%), of which the most frequent was small cell carcinoma. Among the well-differentiated (44%), low-grade (58%) followed by intermediate grade (24%) and low-grade (17%).

Metastases were registered in 37% of the cases with mainly liver involvement (49%), lymph nodes (21%), and central nervous system (9%).

Death occurred in 24% of cases.

Conclusions: The results of the present study coincide with those reported worldwide, highlighting the predominance of tumors of pulmonary origin, as well as similar clinical symptoms according to the affected organs

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Published
2021-10-24
How to Cite
1.
Martínez Montalvo CM, Muñoz Delgado DY, Gómez Ledesma YR, Pérez Hetting MA, Vargas Calderón MD, Ordoñez Muñoz SG, Pinzón Tovar A, Jiménez Sánchez HC. Clinical and demographic characteristics of an adult population with neuroendocrine tumors. Acta Med Peru [Internet]. 2021Oct.24 [cited 2021Dec.5];38(3). Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/2058
Section
BRIEF ORIGINALS