Vitamin D deficiency associated with hyperphosphatemia in children

Keywords: Vitamin D, Vitamin D Deficiency, Hyperphosphatemia, Rickets, Pseudohypoparathyroidism, Parathyroid Hormone, Hypocalcemia, Child

Abstract

Children with vitamin D deficiency can have normal or high phosphorus despite having a high parathyroid hormone test (PTH). Pseudohypoparathyroidism (PHP) is characterized by hyperphosphatemia. The similarity that can occur between vitamin D deficiency associated with hyperphosphatemia and PHP makes it important to review case reports of vitamin D deficiency associated with hyperphosphatemia to understand why this association may occur and what is the relevance of studying the vitamin D level in children with suspected PHP. The aim of this review was to identify reports of children with vitamin D deficiency associated with hyperphosphatemia and to discuss the mechanisms of this association. Reports of 7 children cases were identified. Vitamin D deficiency could reduce the phosphaturic response to elevated PTH. It is concluded that it is important to rule out vitamin D deficiency in all children with suspected PHP

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Author Biography

Manuel André Virú-Loza, Universidad Nacional Mayor de San Marcos

Médico pediatra, Universidad Nacional Mayor de San Marcos

Maestrando en Ciencias en Investigación Epidemiológica, Universidad Peruana Cayetano Heredia

Published
2021-08-23
How to Cite
1.
Virú-Loza MA. Vitamin D deficiency associated with hyperphosphatemia in children. Acta Med Peru [Internet]. 2021Aug.23 [cited 2021Sep.21];38(2). Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/1909