Clinical and serological findings for atypical respiratory infections in asthmatic children in Grau Emergency Hospital, EsSalud, 2007

  • Rómulo Huamaní Egocheaga Hospital Grau EsSalud
  • Javier Miranda Candelario Hospital Grau EsSalud
  • Clara Mejía Vásquez Hospital Grau EsSalud
  • Cecilia Campos Noriega Hospital Grau EsSalud
Keywords: Asthma exacerbation(s), Atypical microorganisms, Children

Abstract

Objective: The objective of this study was to determine the profile of infections caused by atypical microorganisms in children with asthma exacerbations treated in Grau Emergency Hospital during 2007.

Methodology: This is a prospective and cross-sectional study performed in 2007, in which 90 patients between 2 and 14 years old who were brought to the Pediatric Emergency area because of asthma exacerbations refractyory to conventional therapy were included. A blood sample was taken from all patients, in order to perform an ELISA indirect immunoassay test, looking for IgM showing acute infections caused by Chlamydia pneumoniae and Mycplasma pneumoniae.

Results: An overall prevalence of respiratory infections caused by atypical microorganisms was found in 30% (27/90) of children with asthma, 20% (18/90) for Chlamydia pneumoniae, 13.3% (12/90) for Mycoplasma pneumoniae, and mixed infections (M. pneumoniae and C. pneumoniae) in 3.3% (3/90). We also found that infections caused by atypical agents increased in winter (33.3%), while those caused by Chlamydia were prevalent all over the year. There were no significant differences in frequency of these infections with respet to age (being more or less than 5 years old) or sex. More frequent radiological featurees were peribronchial thickening (29.6%), chest hyperinflation (22.2%), and hilar opacities (22.2%). CBCs were reported as nromal in more than 80% of the patients (22/27).

Conclusions: The overall prevalence of atypical microorganisms in children with asthma exacerbations was 30%, and it was independent of age and sex. We must have a high clinical suspicion index for theses conditions in children brought to the ER with history of persistant asthma withy moderate exacerbations refractory to conbventional therapy who also have a normal CBC and a chest X-ray pattern showing peribronchiaal thickening, chest hyperinflation, and hilar opacities.  

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Published
2009-09-29
How to Cite
1.
Huamaní Egocheaga R, Miranda Candelario J, Mejía Vásquez C, Campos Noriega C. Clinical and serological findings for atypical respiratory infections in asthmatic children in Grau Emergency Hospital, EsSalud, 2007. Acta Med Peru [Internet]. 2009Sep.29 [cited 2024Jul.14];26(3):162 -168. Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/1517
Section
ORIGINAL ARTICLES