High-risk human papilloma virus in squamous cell esophageal cancer: a retrospective clinicopathologicalstudy from 2003 to 2006 in Edgardo Rebagliati-Martins Hospital, EsSalud, Lima, Peru

Authors

  • Brady Beltran Gárate Hospital Edgardo Rebagliati Martins
  • Manuel Huamán Guerrero Hospital Edgardo Rebagliati Martins
  • Fernando Osores Plenge Universidad Ricardo Palma
  • Américo Palomino Portilla Hospital Edgardo Rebagliati Martins
  • Alejandro Yabar Berrocal Hospital Edgardo Rebagliati Martins
  • Esther Cotrina Montenegro Centro Peruano de Diagnóstico Molecular
  • Alí Gallo López Universidad San Martin de Porres
  • Marco Lopez Hilasaca Hospital Edgardo Rebagliati Martins

Keywords:

Esophageal squamous cell cancer, Human papilloma virus, High risk

Abstract

Introduction: Human papilloma virus (HPV) is an agent involved in the pathophysiology of cervical cancer. Many reports describe an association between HPV and esophageal squamous-cell carcinoma (ESCC).
Objective: The main objective of the study is to determine the frequency of high-risk HPV infection and ESCC.
Material and method: A retrospective study including 29 ESCC cases with a histological and pathological diagnosis from 2003 to 2006 in Edgardo Rebagliati-Martins Hospital in Lima, Peru. Paraffin-embedded tissue fragments underwent RT-PCR tests for detecting HPV types 16, 18, 31, 33, and 45.
Results: Mean age of patients was 73 years, male to female ratio was 3. Stage I disease was found in one case; stage II disease in 12 cases, stage III disease in 14 cases, and stage IV in 2. No highrigh HPV was found in any of the samples studied, even though we used two different probes.
Conclusion: HPV was not detected in ESCC in the population studied.

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Published

2009-06-30

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SHORT COMMUNICATION

How to Cite

1.
High-risk human papilloma virus in squamous cell esophageal cancer: a retrospective clinicopathologicalstudy from 2003 to 2006 in Edgardo Rebagliati-Martins Hospital, EsSalud, Lima, Peru. Acta Med Peru [Internet]. 2009 Jun. 30 [cited 2025 Jan. 22];26(2):83-5. Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/1499

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