Esclerosis múltiple de alta actividad: ¿se puede iniciar precozmente el tratamiento con drogas de alta eficacia?

  • Charles Huamaní Hospital Nacional Guillermo Almenara.
  • Edgard Rojas Hospital Nacional Guillermo Almenara.
  • José Inca Hospital Nacional Guillermo Almenara.

Abstract

La esclerosis múltiple (EM) es una enfermedad crónica del sistema nervioso central (SNC) que desarrolla cuadros clínicos muy variados, puede progresar con brotes, dejar secuelas entre ellos, y tener un lento curso discapacitante. Sin embargo, en algunas personas los brotes tienen compromiso múltiple del SNC, rápido deterioro de la discapacidad, y otros factores de riesgo de mal pronóstico de la enfermedad. Aunque no hay consenso sobre su definición, estas características indican que estamos ante una EM de alta actividad. Poder identificar la EM de alta actividad de forma precoz nos permite individualizar su tratamiento y usar drogas de alta eficacia. Nosotros describimos la dificultad para conciliar una definición apropiada de M de alta actividad y la necesidad de usar de forma precoz drogas de alta eficacia en aquellas EM de alta actividad que se presentan desde el inicio de la enfermedad.

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Author Biographies

Charles Huamaní, Hospital Nacional Guillermo Almenara.
Servicio de Neurología, Hospital Nacional Guillermo Almenara. Lima, Perú. Médico epidemiólogo . Residente de neurología
Edgard Rojas, Hospital Nacional Guillermo Almenara.
Servicio de Neurología, Hospital Nacional Guillermo Almenara. Lima, Perú. Médico neurólogo
José Inca, Hospital Nacional Guillermo Almenara.
Servicio de Neurología, Hospital Nacional Guillermo Almenara. Lima, Perú. Médico neurólogo

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Published
2018-01-31
How to Cite
1.
Huamaní C, Rojas E, Inca J. Esclerosis múltiple de alta actividad: ¿se puede iniciar precozmente el tratamiento con drogas de alta eficacia?. Acta Med Peru [Internet]. 2018Jan.31 [cited 2024Mar.29];34(4):301-8. Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/463