Clinical Features and Histopathological Findings in Rhupus Patients Developing Glomerulonephritis in Arzobispo Loayza Nacional Hospital Between 2003 and 2009

Authors

  • Gissela Suárez Pichilingue Departamento de Medicina del Hospital Gustavo Lanatta Luján
  • Jorge Gutierrez Campos Hospital Nacional Arzobispo Loayza, Lima
  • Javier Cieza Zevallos Profesor Asociado, Departamento de Medicina, Facultad de Medicina Alberto Hurtado, Universidad Peruana Cayetano Heredia

Keywords:

Glomerulonephritis, Arthritis, rheumatoid

Abstract

Up to 10% of patients with Systemic Lupus Erythematosus have a joint condition similar to that of rheumatoid arthritis, which is called Rhupus. These patients predominantly have signs and symptoms of rheumatoid arthritis and kidney damage associated with Lupus.

Objectives: To describe the clinical characteristics and the renal histopathological findings in patients with rhupus.

Materials and methods: Retrospective review of case reports and kidney biopsies from patients seen from 2003 to 2009 in Arzobispo Loayza National Hospital.

Results: There were 7 patients with rhupus; their median age was 40 years, the median time of disease progression was 2 years. Most relevant renal histopathological findings were type IV glomerulonephritis in 5 patients; proteinuria between 288 to 2560 mg/24 hours and rheumatoid factor titers between14 to 34.6 UI/L were also found.

Conclusions: Patients were older compared to others previously reported previously in the literature. Lupus-related renal damage was moderate to severe.

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Published

2011-06-30

Issue

Section

ORIGINAL ARTICLES

How to Cite

1.
Clinical Features and Histopathological Findings in Rhupus Patients Developing Glomerulonephritis in Arzobispo Loayza Nacional Hospital Between 2003 and 2009. Acta Med Peru [Internet]. 2011 Jun. 30 [cited 2024 Nov. 23];28(2):79-81. Available from: https://amp.cmp.org.pe/index.php/AMP/article/view/1092

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